Safe drug processing and formulation

The pharmaceutical industry requires the utmost care, precision and quality in drug manufacturing and processing.

To ensure total protection from the external environment during product handling, it is important to use special tools and machinery such as isolators and glove boxes for asepsis designed to exclude the entry of contaminants from the outside.

These instruments work under positive pressure and a contained atmosphere, that is, a static climate of high purity, such as argon or nitrogen.

Sterile isolators are able to ensure very high internal sterility, where other operations such as dispensing sterile products or sampling ingredients that require aseptic conditions and transfer of sterile products can be performed. The use of such instruments always results in significant energy savings (compared to the use of large dedicated clean-rooms).

Micronization of API and pharmaceutical excipients

In the pharmaceutical industry, powders are essential in the preparation of granules, tablets and capsules: they can therefore enter the composition of various pharmaceutical forms or represent an actual, stand-alone pharmaceutical formula.

The technique of micronization in the pharmaceutical field is a state-of-the-art system for reducing the particle size of an excipient’s active ingredient in order to meet the required size parameters, which are essential for the formulation of the finished product and necessary for obtaining the desired bioavailability of the same. FPS provides a wide availability of micronization equipment such as to ensure maximum flexibility in terms of quantity and/or activity.

Fine grinding is the mechanical reduction of a coarse solid material into smaller particles.
Containment is the separation of a hazardous area from a clean one by means of a physical (isolators) or aerodynamic (downflow booths) barrier.
Optimization of process parameters and study of the behavior of micronized products