Glossary

Pharmaceutical degradation

Pharmaceutical degradation indicates the inability of a formulation to remain stable within a particular chemical, microbiological, therapeutic, physical, and toxicological specification. This can occur through reversible or irreversible processes, and the most common factors affecting it can be temperature, light, pH, oxidation, and enzymatic degradation. Pharmaceutical degradation is exploited to create robust and accurate methods for the analysis of drugs and related compounds.