The ProMill series is designed to grind large volumes of product, from 2 kg and up, flexibly and efficiently. They are optimized fluid jet mills with low process gas consumption, maximum performance and fast product changeover operations.
All component connections are made to be cGMP compliant and to ensure simple assembly and disassembly operations. The number of components is minimized to also speed up handling, cleaning and validation activities. ProMill series jet mills can be integrated into FPS isolators to enable the processing and handling of sterile or potentially toxic and radioactive products.
The ProMills are available with volumetric or gravimetric feeder, cloth bag separation filter, manual control panel and data recorder compliant to CFR21 Part11.
ProMill series jet mills can be easily integrated into FPS isolators to enable the processing of very active or sterile products. It is also available in an ATEX configuration. Special configurations, such as with PTFE or ceramic inserts and/or coatings, Hastelloy, etc., can be requested.
At FPS MEC Test centre it is possible to perform technical trials with your products and FPS jet mills.
| Name | pro mill - 8 | pro mill -12 | pro mill - 16 |
|---|---|---|---|
| Dimensions | 8" milling chambe | 12" milling chamber | 16" milling chamber |
| Material | AISI316L / PTFE / Ceramic inserts | AISI316L /PTFE / Ceramic | AISI316L / PTFE / Ceramic |
| Gaskets | PTFE - FEP / Viton - silicone | PTFE - FEP / Viton - silicone | PTFE - FEP / Viton - silicone |
| Surface roughness | < 0,25 μm - contact parts < 0,80 μm - non contact parts | < 0,25 μm - contact parts < 0,80 μm - non contact parts | < 0,25 μm - contact parts < 0,80 μm - non contact parts |
| Batch Size | minimum 2 kg - maximum 100 kg | minimum 5 kg - maximum 2500 kg | minimum 20 kg - maximum 5000 kg |
| Productivity | minimum 0,5 kg/h - maximum 80 kg/h | minimum 5 kg/h - maximum 200 kg/h | minimum 10 kg/h - maximum 400 kg/h |
| Gas Consumtpion @ 7 barg | 119 Nm3/h | 249 Nm3/h | 444 Nm3/h |
| Gas Consumtpion @ 12 barg | 205 Nm3/h | 427 Nm3/h | 761 Nm3/h |
| Gas Consumtpion @ 100 psig | 74 SCFM | 155 SCFM | 277 SCFM |
| Gas Consumtpion @ 175 psig | 128 SCFM | 266 SCFM | 474 SCFM |
| Yield | up to 99,95% (depending on batch size) | > 99,5% (depending on batch size) | > 99,5% (depending on batch size) |
| Working pressure | from 2 up to 12 barg | from 2 up to 12 barg | from 2 up to 12 barg |
ProMill-8 is a production scale unit and it is the next step up the scale from research and laboratory units, suitable for micronizing from 500g up to 80Kg/h.
ProMill-12 is a production scale unit, suitable for micronizing up to 200 kg per hour.
Typical batch sizes for using the ProMill-16 air-jet mill range from 20 kg to 5000 kg.
FPS has recently cooperated with pharmaceutical industry experts to research best jet mill practices for pharmaceutical. FPS strongly believes in knowledge sharing and continuous improvement. For this reason, FPS President, Eng. Gianola, and Vice President, Mr Corsini, both experts in milling and micronization technologies, worked with M. Nakach Ph.D on a research published in the Pharmaceutical Development and Technology Magazine. Mr. Nakach works at Sanofi. He […]
FPS is alongside its customers too after system installation and validation and offers them a specific replacement service set off. Our team of experts is able to provide customized spare parts lists to plan the periodic replacement of parts subject to wear, managing the entire life cycle of spare parts. We have decided to dedicate […]
Issues: Particle size reduction down to low micron is needed Operators must be protected because product is very dusty Large campaigns with expensive product: highest productivity is needed High Potent apis will be added in the future “High Potent Ready” solution: Air-tight separation cyclone with WIP to contain dust Modular micronization equipment for easy integration […]
Early drug development is increasingly important, and FPS supports that activity by offering new custom solutions that fit the specific needs of the Pharmaceutical, Biotech and Fine Chemical sectors. What do we mean by isolators for R&D and Pilot Plants? These machines are installed in research laboratories and/or pilot production plants, to ensure safe handling of active substances in […]
