Small batches of product (3g to 100kg) and all demands of laboratory needs can be grinded by the PilotMill series.
The PilotMill series provides maximum flexibility of use and complete scalability of the industrial process: it is the result of an optimization study that minimizes components and provides for connections between them in accordance with cGMPs so as to ensure fast and easy assembly, disassembly and cleaning.
All the Pilot Mills are available with volumetric or gravimetric feeder, cloth bag separation filter, manual control panel and data recorder compliant to CFR21 Part11.
PilotMill series can be easily integrated into FPS isolators to enable the processing of very active or sterile products. It is also available in an ATEX configuration. Special configurations, such as with PTFE or ceramic inserts and/or coatings, Hastelloy, etc., can be requested.
At FPS MEC Test Centre it is possible to perform technical trials with your products and FPS jet mills.
| Name | Pilot Mill - 2 | Pilot Mill - 3 | Pilot Mill - 4 | Pilot Mill - 5 | Pilot Mill - 6 |
|---|---|---|---|---|---|
| Dimensions | 2” milling chamber | 3” milling chamber | 4” milling chamber | 5" milling chamber | 6" milling chamber |
| Material | AISI316L / PTFE / Ceramic inserts | AISI316L / PTFE / Ceramic | AISI316L / PTFE / Ceramic | AISI316L / PTFE | AISI316L / PTFE |
| Gaskets | PTFE – FEP / Viton - Silicone | PTFE – FEP / Viton - Silicone | PTFE – FEP / Viton - Silicone | PTFE - FEP / Viton - silicone | PTFE - FEP / Viton - silicone |
| Surface roughness | < 0.25 μm – contact parts < 0.80 μm – non contact parts | < 0.25 μm – contact parts < 0.80 μm – non contact parts | < 0.25 μm – contact parts < 0.80 μm – non contact parts | < 0,25 μm - contact parts < 0,80 μm - non contact parts | < 0,25 μm - contact parts < 0,80 μm - non contact parts |
| Batch Size | Minimum 2 g - Maximum 5 kg | Minimum 5 g – Maximum 10 kg | Minimum 10 g – Maximum 60 kg | Minimum 100 g - Maximum 100 kg | Minimum 200 g - Maximum 250 kg |
| Productivity | Minimum 10 g/h- Maximum 3 kg/h | Minimum 30 g/h – Maximum 5 kg/h | Minimum 50 g/h – Maximum 10 kg/h | Minimum 0,2 kg/h - Maximum 20 kg/h | Minimum 0,25 kg/h - Maximum 30 kg/h |
| Gas Consumtpion @ 7 barg | 11.6 Nm3/h | 14.4 Nm3/h | 22 Nm3/h | 46,5 Nm3/h | 61,6 Nm3/h |
| Gas Consumtpion @ 12 barg | 19.8 Nm3/h | 24.7 Nm3/h | 37.8 Nm3/h | 79,7 Nm3/h | 105,6 Nm3/h |
| Gas Consumtpion @ 100 psig | 7,2 SCFM | 9,0 SCFM | 13,7 SCFM | 29,0 SCFM | 38,4 SCFM |
| Gas Consumtpion @ 175 psig | 12,3 SCFM | 15,4 SCFM | 23,6 SCFM | 49,7 SCFM | 65,8 SCFM |
| Yield | Typical yield 99.5% depending on batch size | Typical yield 99.5% depending on batch size | Typical yield 99.5% depending on batch size | Typical yield 99.5% depending on batch size | Typical yield 99.5% depending on batch size |
| Working pressure | From 2 up to 12 barg | From 2 up to 12 barg | From 2 up to 12 barg | from 2 up tp 12 barg | from 2 up to 12 barg |
The PilotMill-2 jet mill is designed for small batches of product from 1g to 3kg. Depending on this process condition, PilotMill-2 provides higher micronized product yield. It is available in a top discharge configuration with product recovery inside the filter bag to further maximize product yield.
The PILOTMILL-2 is the result of an unparalleled optimization study that involved the milling chamber, the nozzles and the classifier.
The PilotMill-3 jet mill is suitable for R&D activities and the micronization of product batches starting from 3g and up to about 10kg, ensuring extremely low product loss.
The PILOTMILL-4 jet mill is designed for product development’s needs, where batches from 5g to 60kg are considered. It is available in top and bottom discharge configurations.
PilotMill-5 is the ideal solution for development and production needs in batches from 100g to 100kg.
PilotMill-6 meets product development needs in batches from 500g to 250kg.
A spiral jet mill is a piece of equipment used to reduce the particle size of pharmaceutical and fine chemical powders down to few micrometers. It is made of different components, each designed for a specific part of the micronization process. The product is first poured in a feeder where it is fed into the product line of […]
Early drug development is increasingly important, and FPS supports that activity by offering new custom solutions that fit the specific needs of the Pharmaceutical, Biotech and Fine Chemical sectors. What do we mean by isolators for R&D and Pilot Plants? These machines are installed in research laboratories and/or pilot production plants, to ensure safe handling of active substances in […]
FPS has recently cooperated with pharmaceutical industry experts to research best jet mill practices for pharmaceutical. FPS strongly believes in knowledge sharing and continuous improvement. For this reason, FPS President, Eng. Gianola, and Vice President, Mr Corsini, both experts in milling and micronization technologies, worked with M. Nakach Ph.D on a research published in the Pharmaceutical Development and Technology Magazine. Mr. Nakach works at Sanofi. He […]
FPS has recently delivered a high containment Integrated systems for an Oncology plant in Bangalore. The system is composed by an ANFD discharge Isolator, a Vacuum Transport System (VTS) and a Micronization equipment PROMILL-8 in Isolator. “Our client searched an appropriate solution for -grinding material and clean packaging after the filtering and drying process-“ say […]
